Benchmarking Large Language Models in Biomedical Classification and Named Entity Recognition: Evaluating the Impact of Prompting Techniques and Domain Knowledge

Benchmarking Large Language Models in Biomedical Classification and Named Entity Recognition: Evaluating the Impact of Prompting Techniques and Domain Knowledge

Practical Solutions and Value of Benchmarking Large Language Models in Biomedical Classification and Named Entity Recognition

Research Findings

LLMs in healthcare are increasingly effective for tasks like question answering and document summarization, performing on par with domain experts.

Standard prompting outperforms complex techniques like Chain-of-Thought (CoT) reasoning and Retrieval-Augmented Generation (RAG) in medical classification and Named Entity Recognition (NER) tasks.

Effective integration of external knowledge in LLMs is crucial for real-world applications in healthcare.

Standard Prompting consistently yields the highest F1 scores for classification tasks across all models.

Insights and Recommendations

LLMs face limitations in generalizability and effectiveness in structured biomedical information extraction, requiring better translation of advanced prompting methods to biomedical tasks.

The study emphasizes the need to integrate domain-specific knowledge and reasoning capabilities to enhance LLM performance in real-world healthcare applications.

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